Core Technology

Protein expression and purification

• Vector preparation: construction of commercial plasmid vector

• Design and preparation of multi-tag, insertion, point mutation, point removal and parallel expression vectors

• protein high expression in bacterial, viral and mammalian cells

• Automated protein purification supported by multiple AKTAs

• Protein reprocessing before crystallization: protein renaturation, protein dephosphorylation and deglycosylation

• Protein isotope labeling for NMR

• Membrane protein purification

• Ultra-low endotoxin protein purification (final endotoxin can be as low as 0.1EU/mg)

• DNA purification

• Protein production services

Peptide library construction and screening

• Custom peptide libraries based on known structures

• Based on the structures of known compounds, construct and design a series of peptides in the following ways, including but not limited to, and screen the functions and indications of the target compounds in order to obtain new molecules or new structures with the target efficacy.

• Phage display peptide library

• One-strain, one-species chemical combinatorial peptide library

• DNA-encoded chemical combinatorial peptide library

core technology platform