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Category: Peptides
Most of the polypeptide toxins come from the venom glands of poisonous animals, such as spiders, snakes, scorpions, etc. There are a wide variety of toxin polypeptides, which are highly selective for animal cell ion channels or receptors. Its high specificity makes it often used as an important pharmacological probe to elucidate ion channel subtypes and physiological roles in natural tissues, or as a potential therapeutic drug for research. However, it is difficult to obtain toxin polypeptides by extraction or genetic recombination methods and the amount of acquisition is low, while chemical synthesis can achieve a large amount of toxin polypeptides.
Most of the polypeptide toxins come from the venom glands of poisonous animals, such as spiders, snakes, scorpions, etc. There are a wide variety of toxin polypeptides, which are highly selective for animal cell ion channels or receptors. Its high specificity makes it often used as an important pharmacological probe to elucidate ion channel subtypes and physiological roles in natural tissues, or as a potential therapeutic drug for research. However, it is difficult to obtain toxin polypeptides by extraction or genetic recombination methods and the amount of acquisition is low, while chemical synthesis can achieve a large amount of toxin polypeptides.
ion channels and other receptor proteins on the targeting cell membrane: to influence the structure of membrane proteins, thereby regulating related physiological functions. Such as particle transport processes on ion channel proteins.
● New ion channel subtypes discovered in scientific research, the working mechanism is analyzed through the complex structure with toxins.
● In scientific research, the function of membrane protein is verified by physiological and biochemical experiments, or other research purposes.
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