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CAT | N1010-V |
CAS NO. | 129129-65-3 |
Product Name | μ-conotoxin GIIIA |
Purity | > 98% |
Form/State | Lyophilized powder |
Solubility | Soluble in water |
Molecular weight | 2609 Da |
Molecular formula | C100H170N38O32S6 |
Source | Synthetic peptide |
Storage | Shipped at room temperature. The product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C. |
Storage of solutions | Up to two weeks at 4°C or three months at -20°C. |
Sequence | RDCCTXXKKCKDRQCKXQRCCA(Disulfide bonds between Cys3-Cys15, Cys4-Cys20, and Cys10-Cys21. X = Hydroxyproline. Ala22 – C-terminal amidation) |
μ-Conotoxin GIIIA, a peptide toxin isolated from Conus geographus, preferentially blocks the skeletal muscle sodium channel NaV1.4. GIIIA folds compactly to a pyramidal structure stabilized by three disulfide bonds
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