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Hefei KS-V Peptide Biological Technology Co., Ltd. Hefei KS-V Peptide Biological Technology Co., Ltd.
Hefei KS-V Peptide Biological Technology Co., Ltd.
H2AK13Ub
Products

SPECIFICATION OF H2AK13Ub


CAT

H1401

Product Name

Histone H2A-K13Ub

Purity

≥95% by HPLC analysis

Appearance

White powder

Usage

Research use only

Storage

Shipping at room temperature.

Upon delivery aliquot.

Stored at -20°C or -80°C.

Avoid freeze/thaw cycle.

Sequence

SGRGKQGGKA RAK(Ub)AKTRSSR AGLQFPVGRV HRLLRKGNYA ERVGAGAPVY LAAVLEYLTA EILELAGNAA RDNKKTRIIP RHLQLAIRND EELNKLLGKV TIAQGGVLPN IQAVLLPKKT ESHHKAKGK


APPLICATION OF H2AK13Ub

Histone modifications are associated with distinct transcription states and serve as heritable epigenetic markers for chromatin structure and function. RNF168-mediated ubiquitination of histone H2A Lys13,15 (H2AK13,15ub) at DNA double-strand breaks (DSBs) is crucial for preventing aberrant DNA repair and maintaining genome stability. USP51 is the DUB for H2AK13,15ub and regulates DNA damage response.


  • APPLICATION OF H2AK13Ub
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