SEARCH
ENGLISH
CAT | H2402 |
Product Name | Histone H2BK120Ub |
Purity | ≥95% by HPLC analysis |
Appearance | White powder |
Usage | Research use only |
Storage | Shipping at room temperature. Upon delivery aliquot. Stored at -20°C or -80°C. Avoid freeze/thaw cycle. |
Sequence | PEPAKSAPAP KKGSKKAVTK AQKKDGKKRK RSRKESYSVY VYKVLKQVHP DTGISSKAMG IMNSFVNDIF ERIAGEASRL AHYNKRSTIT SREIQTAVRL LLPGELAKHA VSEGTKAVTK(Ub) YTSSK |
Histone modifications are associated with distinct transcription states and serve as heritable epigenetic markers for chromatin structure and function. H2B-K120ub is a prominent histone posttranslational modification (PTM) associated with the actively transcribed genome. H2B-K120ub act as a signaling hub for several downstream biochemical processes associated with active transcriptional elongation, including lysine methylation events on histone H3, as well as binding of the histone chaperone complex, FACT.
English 