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CAT | H3107 |
Product Name | Histone H3-K27me1 |
Purity | ≥95% by HPLC analysis |
Appearance | White powder |
Usage | Research use only |
Storage | Shipping at room temperature. Upon delivery aliquot. Stored at -20°C or -80°C. Avoid freeze/thaw cycle. |
Sequence | ARTKQTARKS TGGKAPRKQL ATKAARK(me1)SAP ATGGVKKPHR YRPGTVALRE IRRYQKSTEL LIRKLPFQRL VREIAQDFKT DLRFQSSAVM ALQEACEAYL VGLFEDTNLC AIHAKRVTIM PKDIQLARRI RGERA |
H3K27me1 is linked to the promotion of transcription and is seen to accumulate in transcribed genes. Histone-histone interactions play a role in this process. Regulation occurs via Setd2-dependent H3K36me3 deposition. H3K27me1 shows an inverse distribution to H3K27me3 that defines the boundaries between the TP and GRI regions and is diagnostic for constitutive heterochromatin elsewhere in the barley genome. H3K27me1 accumulates within expressed genes and promotes transcription. Setd2-dependent H3K36me3 regulates H3K27me1 versus H3K27me2 intragenic deposition.
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