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Hefei KS-V Peptide Biological Technology Co., Ltd. Hefei KS-V Peptide Biological Technology Co., Ltd.
Hefei KS-V Peptide Biological Technology Co., Ltd.
H3K4me3
Products

SPECIFICATION OF H3K4me3


CAT

H3103

Product 

Name

Histone H3-K4me3

Purity

≥95% by HPLC analysis

Appearance

White powder

Usage

Research use only

Storage

Shipping at room temperature.

Upon delivery aliquot.

Stored at -20°C or -80°C.

Avoid freeze/thaw cycle.

Sequence

ARTK(me2)QTARKS TGGKAPRKQL ATKAARKSAP ATGGVKKPHR YRPGTVALRE IRRYQKSTEL LIRKLPFQRL VREIAQDFKT DLRFQSSAVM ALQEACEAYL VGLFEDTNLC AIHAKRVTIM PKDIQLARRI RGERA




APPLICATION OF H3K4me3

H3K4me3 is commonly associated with the activation of transcription of nearby genes. H3K4 trimethylation regulates gene expression through chromatin remodeling by the NURF complex. This makes the DNA in the chromatin more accessible for transcription factors, allowing the genes to be transcribed and expressed in the cell. More specifically, H3K4me3 is found to positively regulate transcription by bringing histone acetylases and nucleosome remodeling enzymes (NURF). H3K4me3 also plays an important role in the genetic regulation of stem cell potency and lineage. This is because this histone modification is more so found in areas of the DNA that are associated with the development and establishing cell identity.


  • APPLICATION OF H3K4me3
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