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Hefei KS-V Peptide Biological Technology Co., Ltd. Hefei KS-V Peptide Biological Technology Co., Ltd.
Hefei KS-V Peptide Biological Technology Co., Ltd.
H3K56acK122Ub
Products

SPECIFICATION OF H3K56acK122Ub


CAT

H32401

Product Name

Histone H3-K56ac-K122Ub

Purity

≥95% by HPLC analysis

Appearance

White powder

Usage

Research use only

Storage

Shipping at room temperature.

Upon delivery aliquot.

Stored at -20°C or -80°C.

Avoid freeze/thaw cycle.

Sequence

ARTKQTARKS TGGKAPRKQL ATKAARKSAP ATGGVKKPHR YRPGTVALRE IRRYQK(ac)STEL LIRKLPFQRL VREIAQDFKT DLRFQSSAVM ALQEACEAYL VGLFEDTNLC AIHAKRVTIM PK(Ub)DIQLARRI RGERA


APPLICATION OF H3K56acK122Ub

H3 Lys56 acetylation increases the binding affinity of H3 toward two other chaperones CAF-1 and Rtt106. Meanwhile, H3 Lys56 acetylation promotes H3 Lys122 ubiquitination, which weakens the interaction between H3 and Asf1. Subsequently, Lys56 acetylation and Lys122 ubiquitination synergistically facilitate the transfer of the H3–H4 dimer from the H3–H4–Asf1 complex to other chaperones for (H3–H4)2 tetramer formation and deposition.


  • APPLICATION OF H3K56acK122Ub
KS-V PEPTIDE — PROVIDES THE BEST PEPTIDE SOLUTION.