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Hefei KS-V Peptide Biological Technology Co., Ltd. Hefei KS-V Peptide Biological Technology Co., Ltd.
Hefei KS-V Peptide Biological Technology Co., Ltd.
H3K79me2
Products

SPECIFICATION OF H3K79me2


CAT

H3114

Product Name

Histone H3-K79me2

Purity

≥95% by HPLC analysis

Appearance

White powder

Usage

Research use only

Storage

Shipping at room temperature.

Upon delivery aliquot.

Stored at -20°C or -80°C.

Avoid freeze/thaw cycle.

Sequence

ARTKQTARKS TGGKAPRKQL ATKAARKSAP ATGGVKKPHR YRPGTVALRE IRRYQKSTEL LIRKLPFQRL VREIAQDFK(me2)T DLRFQSSAVM ALQEACEAYL VGLFEDTNLC AIHAKRVTIM PKDIQLARRI RGERA





APPLICATION OF H3K79me2

Lysine 79 of histone H3 can be mono-, di- or trimethylated by Dot1 methylase; methylation at this residue acts as a marker of inactive chromatin regions that are critical for transcriptional silencing, and it is thought that silencing proteins such as Sir3 function by blocking Dot1 methylation. DOT1L-mediated H3K79me2 modification drives cardiomyogenesis through the definition of a specific transcriptional landscape.


  • APPLICATION OF H3K79me2
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