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Hefei KS-V Peptide Biological Technology Co., Ltd. Hefei KS-V Peptide Biological Technology Co., Ltd.
Hefei KS-V Peptide Biological Technology Co., Ltd.
H3T118ph

SPECIFICATION OF H3T118ph


CAT

H3302

Product Name

Histone H3-T118ph

Purity

≥95% by HPLC analysis

Appearance

White powder

Usage

Research use only

Storage

Shipping at room temperature.

Upon delivery aliquot.

Stored at -20°C or -80°C.

Avoid freeze/thaw cycle.

Sequence

ARTKQTARKS TGGKAPRKQL ATKAARKSAP ATGGVKKPHR YRPGTVALRE IRRYQKSTEL LIRKLPFQRL VREIAQDFKT DLRFQSSAVM ALQEACEAYL VGLFEDTNLC AIHAKRVT(ph)IM PKDIQLARRI RGERA



APPLICATION OF H3T118ph

Histone modifications are associated with distinct transcription states and serve as heritable epigenetic markers for chromatin structure and function. H3T118ph alters nucleosome dynamics and remodeling. H3T118ph dramatically decreases DNA–octamer binding increases nucleosome sliding and increases DNA accessibility near the nucleosome dyad. H3T118ph may function to destabilize nucleosomes in vivo by regulating their mobility, disassembly, and remodeling.


  • APPLICATION OF H3T118ph
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