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Hefei KS-V Peptide Biological Technology Co., Ltd. Hefei KS-V Peptide Biological Technology Co., Ltd.
Hefei KS-V Peptide Biological Technology Co., Ltd.
H4K5ac
Products

SPECIFICATION OF H4K5ac


CAT

H4205

Product Name

Histone H4-K5ac

Purity

≥95% by HPLC analysis

Appearance

White powder

Usage

Research use only

Storage

Shipping at room temperature.

Upon delivery aliquot.

Stored at -20°C or -80°C.

Avoid freeze/thaw cycle.

Sequence

SGRGK(ac)GGKGL GKGGAKRHRK VLRDNIQGIT KPAIRRLARR GGVKRISGLI YEETRGVLKV FLENVIRDAV TYTEHAKRKT VTAMDVVYAL KRQGRTLYGF GG


APPLICATION OF H4K5ac

H4K5 is acetylated by TIP60 and CBP/p300 proteins. CAP/p300 open transcriptional start site chromatin by acetylating histones. H4K5ac has also been implicated in epigenetic bookmarking which allows gene expression patterns to be faithfully passed to daughter cells through mitosis. Important cell-type-specific genes are marked in some way that prevents them from being compacted during mitosis and ensures their rapid transcription. H4K5ac appears to prime activity-dependent genes expressed during learning.


  • APPLICATION OF H4K5ac
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