CAT | U2401 |
Product Name | K27-Diubiquitin |
Purity | ≥95% by HPLC analysis |
Appearance | Lyophilized powder |
Usage | Research use only |
Storage | Shipping at room temperature. Upon delivery aliquot. Stored at -20°C or -80°C. Avoid freeze/thaw cycle. |
K27-linkage poly-ubiquitination plays important role in DNA damage repair and autoimmunity. Recently reports have emerged that place K27 chains mainly in the intracellular innate immune response pathway, where they regulate several essential infection sensors, such as STING, cGAS, MAVS, and MDA5, or effectors such as NEMO and Beclin.