Name: Met1 Diubiquitin
Brand: Hefei KS-V Peptide Biological Technology Co., Ltd.

Custom Peptide
Antigenic Peptide
Peptide Probe
API
- KSVP APIs
Ubiquitins
- Ubiquitins and Ubiquitin Probes of KSVP
  - Ubiquitin
  - Ubiquitin Probe
Peptide Toxin
- Peptide Toxin of KSVP
Cosmetic Peptide

SPECIFICATION OF Met1 Diubiquitin

CAT	U2101
Product Name	Met1-Diubiquitin
Purity	≥95% by HPLC analysis
Appearance	Lyophilized powder
Usage	Research use only
Storage	Shipping at room temperature. Upon delivery aliquot. Stored at -20°C or -80°C. Avoid freeze/thaw cycle.

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APPLICATION OF Met1 Diubiquitin

Met1-linked ubiquitin chains are key regulators of inflammation and immunity to pathogens. Met1-linked ubiquitin chains are assembled by LUBAC and are disassembled by the deubiquitinases OTULIN and CYLD. Met1-linked ubiquitin chains function as kinase scaffolds to control signaling outcomes by pattern recognition receptors and cytokine receptors. Intracellular bacteria are decorated with Met1-linked ubiquitin chains for activation of xenophagy. Pathogen-encoded effectors target the Met1-linked ubiquitin machinery to subvert host-defense responses.