SPECIFICATION OF Ub ACC

CAT	U1020
Product Name	Ub-ACC
Purity	≥95% by HPLC analysis
Appearance	Lyophilized powder
Usage	Research use only
Storage	Shipping at room temperature. Upon delivery aliquot. Stored at -20°C or -80°C. Avoid freeze/thaw cycle.

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APPLICATION OF Ub ACC

Ubiquitin-ACC is a fluorogenic substrate for a wide range of deubiquitinating enzymes (DUBs), including ubiquitin C-terminal hydrolases (UCHs) and ubiquitin-specific proteases (USPs). It is a particularly useful reagent for the study of deubiquitinating activity where detection sensitivity or continuous monitoring of activity is essential. DUB assays using UCH-L3, OTUD2, and USP30 demonstrated that Ub-ACC shows nearly 2-fold higher sensitivity than Ub-AMC.