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CAT | U1010 |
Product Name | Ub-AMC |
Purity | ≥95% by HPLC analysis |
Appearance | Lyophilized powder |
Usage | Research use only |
Storage | Shipping at room temperature. Upon delivery aliquot. Stored at -20°C or -80°C. Avoid freeze/thaw cycle. |
Introduction | Ubiquitin-AMC is a fluorogenic substrate for a wide range of deubiquitinating enzymes (DUBs), including ubiquitin C-terminal hydrolases (UCHs) and ubiquitin-specific proteases (USPs). It is a particularly useful reagent for the study of deubiquitinating activity where detection sensitivity or continuous monitoring of activity is essential. |
Can be used for the following applications:
1. Substrate for deubiquitinylating enzyme activity assays.
2. Identification/confirmation of enzyme deubiquitinylation activity.
3. Investigation of deconjugating enzyme-substrate specificity in comparison with alternative UBL substrates.
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